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The Rosette AK Series is a brand that delivers uncompromising quality for reliable results in the treatment of skin problems. Backed by many years of foundational research under the guidance of dermatologists, our products are designed to support the doctors who regularly treat atopic dermatitis and other difficult skin conditions.

Trusted development from
medical institutions and experts

Benefits of natural ceramides

The galactosyl ceramide that makes up the key component of natural ceramides rebuilds the lamellar structures found in intercellular lipids

Product development guided by medical experts

The Rosette AK Series was developed under the guidance of dermatologists as a powerful moisturizing skincare product containing natural ceramides

The role of ceramide

The surface of the skin has a protein layer called the stratum corneum. The spaces between cells in the stratum corneum contain a lipid called ceramide. Ceramide is an intercellular lipid that is created during the process of cell turnover, and contains about 30% moisture. It acts as the glue that holds cells together. When the skin is rich in ceramide, the stratum corneum stays moist for hydrated, dewy skin.

Atopic dermatitis, on the other hand, is known to involve extreme ceramide deficiency. We also lose ceramide as we age, causing moisture to readily evaporate from the surface of the skin during the colder months when we don't sweat.

Ceramide keeps the outer layers of skin healthy and serves a so-called barrier function. When the epidermis is healthy, it locks in moisture and keeps antigens (allergy-causing agents like mites and dust) from infiltrating the skin. It also protects against more general environmental irritants. However, because people with atopic dermatitis lack sufficient ceramide, the barrier function is weakened. Moisture readily escapes from within the skin, drying it out and allowing antigens to enter. Once these irritants have penetrated the skin, they trigger an allergic reaction that results in various forms of inflammation.

Atopic dermatitis is also referred to as “extremely dry skin”. For this reason, in addition to pharmaceutical treatments to inhibit skin inflammation, it is important that patients follow a skincare regimen that focuses on replenishing the ceramides needed to alleviate dry skin and enhance barrier function.

What is the natural ceramide in the Rosette AK Series?

To ensure that our products are safe to use even by patients struggling with atopic dermatitis, the Rosette AK Series contains horse sphingolipid, which is a natural ceramide extracted from fresh spinal marrow of healthy horses. This natural ceramide contains over 70% galactosyl ceramide as well as an excellent balance of sphingomyelin, phosphatidylethanolamine, lecithin, cholesterol, and other nutrients to enhance skin's barrier function and help it retain moisture.

Healthy skin
Dry, inflamed skin resulting from atopic dermatitis

Authorize by ROSETTE Co., Ltd.